Feedback stabilization of a micro droplet in an optical trap
The project consists of building an optical trap and conducting position measure- ments of the droplet as a function of laser power. In a second step, a PID feedback loop will be implemented to actively stabilize the trap.
Investigating protein-metabolite interactions in E. coli
In this project, you will selectively perturb metabolite concentrations inside growing E. coli cells and characterize the dynamic metabolic response using state-of-the-art metabolomics techniques.
Biology of the cell nucleus (Prof. Karsten Weis)
General research topics of the lab: Nuclear organization, Intracellular transport between the nucleus and the cytoplasm, Nuclear pore structure and function, mRNA transport and degradation.
Mechanisms of asymmetric cell division (Prof. Yves Barral)
The laboratory studies the cell division process as a paradigm how cells control their spatio-temporal organization and coordinate complex architectural processes with each other.
DNA repair and Genome stability (Prof. Joao Matos)
Our group uses a combination of approaches (proteomics, biochemistry, cell biology and genetics) and model systems (budding yeast and human tissue culture) to investigate how cells rewire the recombination machinery.
Macromolecular machines mediating bacterial cell-cell interactions (Prof. Martin Pilhofer)
The lab investigates macromolecular complexes that generate order and bridge between the angstrom-scale of atoms, the nanometer-scale of macromolecular assemblies and the micron-scale of entire cells.
Computational single cell biology (Prof. Manfred Claassen)
We aim at elucidating the composition of heterogeneous cell populations and how these implement function in the context of cancer and immune biology by jointly evaluating single cell and genome wide measurements.
RNAi and Genome Integrity (Prof. Constance Ciaudo)
Determine the fundamental genetic/biochemical mechanisms that regulate genome integrity through the study of transposable elements and RNA interference pathways and by exploiting the ES cell system as an in vitro model for differentiation and development.

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