Establishment of a Novel Experimental System for AFM-based Biophysical Membrane Fusion and Curvature Measurements
• Discover the basic working principles of cells and synapses. • Develop new tools to study them.
Multimaterial 3D Printing at the Microscale
3D printing is a family of emerging techniques for fabrication of functional devices. We are currently exploring methods to expand the range of printable materials, such as metals and polymers. Extending the range of materials will automatically lead to new opportunities for fabrication of functiona
Materials characterisation and modelling of ideal dynamic covalent hydrogels
Dynamic covalent hydrogels are increasingly used as tuneable cell culture scaffolds, viscosity modifiers for food and industrial applications, and as injectable drug delivery systems owing to their reversible and mouldable nature. In this project, we aim to characterize and model the mechanical properties of ideal dynamic networks. Students will investigate both bulk properties and microscopic behaviour at the junctions of the materials, through dynamic mechanical analysis and different spectroscopic methods. Finally, students will explore different theoretical and computational modelling approaches to link the microscopic behaviour of the binding pairs that form the cross-links to the viscoelastic properties of ideal dynamic covalent networks.
Piezoelectric energy harvester from AC magnetic fields
Microrobots propelled with AC Magnetic fields are promising candidates for precise minimally-invasive microsurgeries. In this project we will design and fabricate a microharvester based on piezoelectric polymer beams.
Permanent magnetic microrobots for targeted drug delivery
Magnetic microrobots have the potential to revolutionize existing therapeutic and diagnostic procedures. The aim of this project is to design and micro fabricate magnetic micro carriers for targeted drug delivery.
Magnetic Nanowires For Targeted Drug Delivery
The Multi-Scale Robotics Lab is developing and investigating magnetic nanowires for targeted drug delivery. The aim of this project is to design and fabricate magnetic nanowires that can be used for targeted drug delivery assisted by a 5DOF magnetic manipulation system.
Wearable Sensors For Fitness Monitoring
There is a growing interest in fitness trackers and apps monitoring health. Most of them rely on accelerometer and GPS data which do not provide reliable measurements. Direct force and pressure sensors can overcome these issues and revolutionize fitness monitoring.
Closed-loop control of drug delivery
The Langer lab and Traverso lab at MIT currently have several opening positions for students who are interested in interdisciplinary research in translational medicines. We are pushing the frontier of translational medicine by bridging the gap between engineering and clinical medicine.
Biomaterial models to investigate skin diseases
Atopic dermatitis (AD) is a chronic inflammatory skin disease that is characterized by itchy, eczematous skin due to a skin barrier defect and hyper-sensitivity to environmental conditions. AD affects 15–30% of children and 2–10% of adults in developed countries making it one of the most common skin
Skilled synthetic chemist for Biomaterial synthesis in a Medtech startup (Internship or master thesis)
Do you look for a internship to get your first working experience? Would you like to work in a young, fast-moving startup in a highly-diverse, motivated team? Would you like to do lab work, which will turn into a real product to improve peoples life? Then contact us!
FDM 3D-PRINTING OF RECYCLABLE SILICONE
Reversible covalent chemistry is a potentially powerful tool to confer a thermoset material the reprocessability of a thermoplastic. In this project the network of silicone rubbers will be enriched with reversible covalent bonds to obtain crosslinked yet reprocessable (and 3D-printable) materials.
Design and Realization of a Novel Actuator for Implantable Pulsatile Artificial Hearts
Design of an implantable actuation system for a soft total artificial heart.
Interdisciplinary Product Development
Student thesis in drug-delivery materials for health care application with strong focus on prototyping and testing
Mass Transport Across Atomically-Thin Nanoporous Membranes
Selective transport across nanopores is present in fields ranging from water purification & desalination to gas separation and transport across biological channels. We study various transports across nanopores at the limit of membrane thinness with the single-atom-thin membrane material graphene
Designer Hydrogels to Probe Bone Mechanobiology
Living tissues remodel themselves to adapt to their mechanical environment using self-assembled fibrillar proteins. By contrast, conventional synthetic materials lack this property. This project aims to build self-assembled, mechano-responsive fibrillar gels to study bone mechanobiology.
Magnetic-field controlled electrocatalytic reactions
In this project, a student will be responsible for the synthesis of magnetoelectric core-shell nanoparticles and the electrochemical analysis of magnetic-field induced electrocatalytic reactions. A student will have a chance to be a co-author of the following journal papers.
Investigation of brain vasculature and proteinopathies in transgenic mouse models of Alzheimer's disease
Here we aim to investigate the relation between brain vasculature abnormality and amyloid/tau deposits in mouse models of Alzheimer's disease using novel high-resolution fluorescence microscopy.
3-Dimensional Printing of Novel Biomimetic Tympanic Membrane Grafts
Surgery to correct perforations of the tympanic membrane (TM) typically uses autologous graft materials with suboptimal healing and hearing outcomes, partly due to inconsistent material architecture. Our team is developing novel 3D-printable biodegradable grafts to improve hearing and healing outcom
Investigating the structure and properties of metal/ceramic interfaces by means of atomistic simulations: Designing an interatomic potential for the Cu/AlN system
Metal/ceramic interfaces are of great techn. importance. Experiments revealed anomalous fast diffusion of Cu along interfaces between Cu and AlN, which could be exploited for nanojoining technologies. The project aims to investigate the dynamics of such interfacial phenomena by atomistic simulations
Scientist or engineer for Biomaterial development in a Medtech startup
Do you look for a internship to get your first working experience? Would you like to work in a young, fast-moving startup in a highly-diverse, motivated team? Would you like to do lab work, which will turn into a real product to improve peoples life? Then contact us!
Ribozymes investigated by single-molecule FRET
Our focus lies on the visualization of the splicing process of a catalytic RNA that takes place during RNA maturation. The ribozyme of our interest is evolutionary related to the eukaryotic spliceosome.
Solid-state deracemisation via temperature cycles: effect of initial and operating parameters
Deracemisation via temperature cycles is a technique applied for the purification of chiral molecules, e.g. enantiomers (mirror images of each other). Starting from a racemic suspension (enantiomeric excess, ee, equals zero), due to several phenomena occurring (crystal dissolution and growth, agglom
Novel Sensor for Neural Recordings: Electrochemical Investigation of Fundamental Limits
Recent proof of concept tests demonstrated our new sensor can be used for extracellular electrophysiology. While the basic physics underlying the sensor are understood, the particulars & their relation to performance are less so. This project aims to discover the physical limitations of our sensor.
Electrochemical biosensor for low cost diagnostics
Electrochemistry offers a low cost approach to quantitative biosensing which is needed in many diagnostic applications. Therefore, it is often desirable to perform an electrochemical readout on an assay. You will improve the detection limit of such a sensor in this thesis.
Development of electrospun membranes for nanoparticle transport studies at biological barriers
With the growing use of nanotechnology, our body is likely to be exposed to nanoparticles (NPs). Therefore, studies dealing with the translocation and effects of NPs at various biological tissue barriers are of key importance for the safe design of NPs for medical and industrial applications
Master's thesis opportunity: Improving the taste of plant-based foods
This project focuses on the study of the interactions between plant proteins and saliva that lead to the perception of off-flavors in plant-based foods such as meat and milk alternatives.
Novel Bioink Synthesis for 3D Bioprinting
3D bioprinting is a state of the art additive manufacturing technique that has revolutionized tissue engineering strategies. The goal of this project is to design a bioink, compatible with bioprinting able to support the formation of cell secreted collagen.
Copper-catalyzed direct carbozylation of C-H bonds with carbon dioxide – a mechanistic gas-phase study
Mechanistic investigation of the carbon dioxide C-H bond insertion catalyzed by copper.
3D-Printed mini-Bone-Organs
Existing tissue engineering strategies often fail to recreate the complex architecture of bone tissues where 3D networked bone cells reside. This project aims to apply high-resolution 3D-printing to sculpture mini-bone-organs within 3D living microenvironments.
DNA Aptamer-Based Electronic & Plasmonic Sensors for Neurotransmitter Biosensing from Neuronal Networks
Integrating DNA-based biorecognition elements termed aptamers that recognize chemical targets with high specificity and selectivity into next-generation electronic, plasmonic, and optical biosensors.
Material formulation for a novel foaming technology
We are looking for highly motivated students to join our recently awarded ETH Pioneer Fellowship project on alternative foaming agents for bio-based plastics. We use a low temperature high-pressure foaming technology for enhancing mechanical properties of bio-based materials.
Production and Mechanical Properties Characterization of Granular Hydrogels
This project involves in depth study on the mechanical behavior of granular hydrogel materials to enable the production of dynamic tissue engineering scaffolds.
Developing single protein sensors for diagnostics
Technologies that allow for the sensing of single biomolecules (e.g. proteins) which are related to deseases like Alzheimers or cancer are needed to improve future research, diagnostics, and treatment. This work will allow students of different backgrounds to apply their knowledge in biosensing.
PhD positions in cold and controlled chemistry / chemical physics
Two PhD positions are available in the research group of Prof. Stefan Willitsch, University of Basel, Switzerland on the topic of cold and controlled chemistry and collisions.
Student Research Assistant
Functional coatings for gas sensing
Chemical sensing platform for in-situ and real-time monitoring of wound healing process
Chronic wounds (i.e. venous, diabetic ulcers) are regarded as a silent epidemic, which affects 1-2% of the population and represent 2-4% of healthcare expenses. On the other side, approximately 900 mil-lion people suffer worldwide from acute injuries (i.e. penetrating trauma, burns) requiring specia

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