Design and Characterisation of Soft Artificial Hearts
We are looking for students (particularly in an engineering discipline) to work toward designing various features of our soft artificial heart, and other anciliary aspects such as systems control and actuation.
Materials characterisation and modelling of ideal dynamic covalent hydrogels
Dynamic covalent hydrogels are increasingly used as tuneable cell culture scaffolds, viscosity modifiers for food and industrial applications, and as injectable drug delivery systems owing to their reversible and mouldable nature. In this project, we aim to characterize and model the mechanical properties of ideal dynamic networks. Students will investigate both bulk properties and microscopic behaviour at the junctions of the materials, through dynamic mechanical analysis and different spectroscopic methods. Finally, students will explore different theoretical and computational modelling approaches to link the microscopic behaviour of the binding pairs that form the cross-links to the viscoelastic properties of ideal dynamic covalent networks.
Closed-loop control of drug delivery
The Langer lab and Traverso lab at MIT currently have several opening positions for students who are interested in interdisciplinary research in translational medicines. We are pushing the frontier of translational medicine by bridging the gap between engineering and clinical medicine.
Master Thesis on Investigating the structure and properties of metal/ceramic interfaces by means of atomistic simulations: Designing an interatomic potential for the Cu/AlN system
Metal/ceramic interfaces are of great techn. importance. Experiments revealed anomalous fast diffusion of Cu along interfaces between Cu and AlN, which could be exploited for nanojoining technologies. The project aims to investigate the dynamics of such interfacial phenomena by atomistic simulations
3D-Printed mini-Bone-Organs
Current tissue engineering strategies fail to recreate the complex architecture of bone where 3D interconnected osteocytes reside in the lacuno-canalicular system to sense mechanical signals to regulate bone remodeling. We aim to create 3D-printed living osteocyte networks as mini-bone-organs.
Biomaterial models to investigate skin diseases
Atopic dermatitis (AD) is a chronic inflammatory skin disease that is characterized by itchy, eczematous skin due to a skin barrier defect and hyper-sensitivity to environmental conditions. AD affects 15–30% of children and 2–10% of adults in developed countries making it one of the most common skin
Nanoscale 3D printing of functional devices: nanorobots, sensors, energy storage
3D printing is a family of emerging techniques for fabrication of functional devices. We are currently exploring a new technology we developed to achieve 3D nanoprinting with ultrahigh resolution and nanoscale precision. This opens numerous exciting opportunities for fabrication of functional devices and materials for biomedical, sensing and energy storage applications.
Effect-based toxicity tests with cyanobacterial toxins
Our ecosystems and drinking water resources are vulnerable not only to anthropogenic pollutants but also to natural toxins. Among the diverse array of known natural toxins, those produced by aquatic organisms such as cyanobacteria (blue green “algae”) are of particular concern to the integrity and s
Evaluation of the wound healing potential of amnion-derived cells in vitro
The preservation of intact fetal membranes (FM) throughout pregnancy is key for the development of a healthy fetus and newborn. We here propose to test the wound healing response of amnion-derived cells in a three-dimensional in vitro cell culture model and evalute it by different techniques.
Assay developement for cancer diagnostics
You will develop a diagnostic test for testicular cancer. The focus of the project will be on creating the biochemical protocols for the test. The project is in collaboration with a prelaunch startup and a hospital (USZ). Therefore, it is ideal for motivated students who want to have a direct impact
Pressure-Driven Suspension Transfer for the Design of a Novel Continuous Crystallizer
Experimental Analysis of Pressure-Driven Suspension Transfer for the Design of a Continuous Crystallization Setup
Elaboration of sustainable activated carbons
The aim of this project is to explore the properties of a sustainable waste-sourced activated carbon by tailoring its microstructure to fit an application in waste-heat utilization for the next generation of heat pumps.
Develop a diagnostic biosensor
Develop a low-cost and sensitive diagnostic biosensor. You will work on a new sensor technology applicable for various diseases including cronic diseases, cancer or covid-19. The project is ideal for skilled students who are passionate to work on an interdisciplinary project with immediate impact.
Permanent magnetic microrobots for targeted drug delivery
Magnetic microrobots have the potential to revolutionize existing therapeutic and diagnostic procedures. The aim of this project is to design and micro fabricate magnetic micro carriers for targeted drug delivery.
Wearable Sensors For Fitness Monitoring
There is a growing interest in fitness trackers and apps monitoring health. Most of them rely on accelerometer and GPS data which do not provide reliable measurements. Direct force and pressure sensors can overcome these issues and revolutionize fitness monitoring.
Product Develop. in nanoparticle start-up
Mechanical engineering thesis in nanoparticle science with industry and strong focus on development and prototyping
Inferring cellular responses to iron nanomedicines through data analysis
The project will explore responses to medical nanoparticles, with a focus on intravenous nanomedicines used for the treatment of iron deficiency. Analysis of data generated with the advanced blood vessel system will give an insight into cellular pathways that define a response to treatments
Master Thesis on Solid-State Lithium-Ion Microbatteries
Development of thin-film lithium-ion microbatteries for better power performance and for enabling new applications. Tailored project to the background and interests of the student.
DNA-Based Biosensing for In-Vitro and In-Vivo Applications
Developing the next generation of electronic biosensors to detect neurochemicals released by in vitro neuronal networks and biomarkers in clinically relevant human fluids. These novel biosensors will help us answer relevant neuroscience questions and human health concerns. The project will involve the design and development of chemical and electrical platforms as well as functionalization of biomolecules to perform analytical measurements.
Design of a robust heating system for infusion fluids
Patients, especially those rescued after exposure in high mountains or cold water are at risk of hypothermia. Stabilizing patient temperature is critical for medical staff, who work outside the usual hospital environment. In the last years, we have worked on an industrial project on the development
Bidirectional Flow Field for Separation of Molecules and Particles
We are currently studying the use of the bidirectional flow field as a mechanism to separate molecules and particles based on their diffusivities, investigating the effect of the liquid properties (pH and ionic concentration) on the separation performance. Further, we will explore alternative strate
Student Research Assistant
Functional coatings for gas sensing
Chemical sensing platform for in-situ and real-time monitoring of wound healing process
Chronic wounds (i.e. venous, diabetic ulcers) are regarded as a silent epidemic, which affects 1-2% of the population and represent 2-4% of healthcare expenses. On the other side, approximately 900 mil-lion people suffer worldwide from acute injuries (i.e. penetrating trauma, burns) requiring specia

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